Effectiveness of mind body intervention on subfertile females: An approach to accesses oocyte quality

Abstract

Introduction: In recent times, there is a much greater emphasis on the physical causes of infertility so that psychological effects can be ignored. There are, of course, a number of physical and emotional factors that can induce infertility. Mind and body interventions are efficient in lowering psychological distress thereby increases the ART success rate, fetal outcome by improving the psychological and physiological stress. The purpose of the current study is to assess the relationship between effect of mind body intervention and serum cortisol level and oocyte quality. Aim and Objectives: To study the effectiveness of mind body intervention on oocyte quality and serum cortisol level in subfertile females. Materials and Method: This study is done in wardha test tube baby centre AVBRH (SAWANGI) WARDHA Relevant data on the demographics and treatment history as well as the indications for IVF treatment will be recorded. Serum cortisol level of all participant were analysed and then stimulated using a routine short antagonist protocol. Observation and Result: From total recruited patient, one didn’t attended intervention program at all. Four patients attended intervention program from 4 to 6 week in discontinuation manner. Eight patients attended up to 70% to 90% of intervention program and remaining 24 patients attended complete 10 week mind body intervention program. In group of 7 to 9 week intervention 6 patient out of 8 showed decrease in serum cortisol level. Patient who attended complete 10 weeks intervention they are showing significant decrease in serum cortisol level. From 40 patient, 24 attended complete 10 week mind body intervention, among them 16(66%) gave positive response to mature oocyte retrieval. Discussion: In this research, a mind body intervention on subfertile females was created and to see their response to mature oocyte in IVF study. Study revealed that, there were very few studies examined the role of cortisol in relation to M II oocyte and finally clinical pregnancy outcomes. Two studies reported that pregnancy rates were enhanced by adopting the MBI. This is in support to our study. Conclusion: This study concludes that, there is direct correlation of serum cortisol level and oocyte quality and Mind-Body intervention is key factor to improve oocyte quality.