Transmission of hemagglutinin D222G mutant strain of pandemic (H1N1) 2009 virus

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Abstract

A pandemic (H1N1) 2009 virus strain carrying the D222G mutation was identified in a severely ill man and was transmitted to a household contact. Only mild illness developed in the contact, despite his obesity and diabetes. The isolated virus reacted fully with an antiserum against the pandemic vaccine strain.

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Puzelli, S., Facchini, M., Spagnolo, D., de Marco, M. A., Calzoletti, L., Zanetti, A., … Donatelli, I. (2010). Transmission of hemagglutinin D222G mutant strain of pandemic (H1N1) 2009 virus. Emerging Infectious Diseases, 16(5), 863–865. https://doi.org/10.3201/eid1605.091858

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