Queratitis fúngica: Revisión actual sobre diagnósticoy tratamiento

Abstract

Fungal keratitis is a characteristic infection upon tropical zones, associated withvegetaltrauma. Doubt exists about the best diagnostic test and the effectivenessof available treatment. Which is the best diagnostic method for fungal keratitis? And, which is the best management? Fungal culture remains as diagnostic goldstandard of fungal elements. As of treatment, natamycin and amphotericin B arethe most popular drugs for fungal keratitis and they have not shown effectiveness inrandomized controlled trials or systematic reviews. Voriconazole showed effectivenessand security in multiple fungal infections. It may be the drug of choice in optimalconditions, because of its better ocular penetration and wider coverage. However, its high price difficult general application. This review establishes managementrecommendations and the need to perform studies that address cost-effectivenessanalysis of voriconazole for fungal keratitis.