Methyl 4-(4-chlorophenyl)-8-iodo-2-methyl-6-oxo-1,6-dihydro-4H-pyrimido[2, 1-b]quinazoline-3-carboxylate

Abstract

In the title compound, C20H15ClIN3O 3, the dihedral angle between the quinazolinone ring system [r.m.s. deviation = 0.047(2)Å] and the pendant benzene ring is 82.63(11)°. The molecular conformation is stabilized by intramolecular C - H⋯O interactions. In the crystal, the molecules are linked by N - H⋯O hydrogen bonds into chains along the a-axis direction. Another set of chains propagating along [101] is formed due to intermolecular I⋯Cl short contacts of 3.427(1)Å, thus giving layers parallel to (010). The layers are connected by C - H⋯π and π-π interactions, the shortest distance between the centroids of aromatic rings being 3.8143(16)Å.