The Relationship Between Obesity and Level of Polycystic Ovary Syndrome (PCOS): Literature Review

Abstract

Polycystic ovary syndrome (PCOS) is a condition related with genetics, obesity, insulin resistance, and hyperandrogen causes menstrual irregularities, oligo-ovulation or anovulation, infertility, metabolic disorders and others. Obesity has a negative impact on reproductive organs make functional changes from the HPO axis, obese women also have high insulin levels and increase in androgen production. This study to determine the relation between obesity and the incidence of PCOS. The research design is literature review conducted based on the results of searching scientific articles on the Google Scholar, Science Direct and PubMed databases, using the keywords "obesity" OR "overweight" AND "prevalence of PCOS". Obtained 15 scientific articles according to the inclusion criteria, can be analyzed. The conclusion there is a relationship between PCOS and obesity, this correlates with increase in IR and hyperandogens. Prevalence of BMI and weight gain increased in women with PCOS. Obese women with hyperandrogen increase the risk of PCOS.