Erythrodermic psoriasis with regression after prophylaxis with isoniazid and antidepressant therapy - Case report

Abstract

An 83 year old woman, exhibiting severe psoriasis, was treated conventionally (phototherapy, acitretin, and cyclosporine). After poor clinical results and significant changes in laboratory procedures, those treatments were suspended. She was then being prepared to be submitted to biological treatment, when preliminary results disclosed a 30mm PPD. Complete improvement occurred [only] after introducing prophylactic therapy for tuberculosis and anti-depressive medication. © 2011 by Anais Brasileiros de Dermatologia.