Non-adherence in type 2 diabetes: Practical considerations for interpreting the literature

Citations of this article
Mendeley users who have this article in their library.


The rising prevalence of type 2 diabetes poses a serious threat to human health and the viability of many health care systems around the world. Although several prescription medications can play a vital role in controlling symptoms and preventing complications, non-adherence to these therapies is highly prevalent and has been linked to increases in morbidity, mortality, and health care costs. Although a vast array of significant adherence predictors has been identified, the ability to explain or predict non-adherence with known risk-factors remains poor. Further, the definitions, outcomes, and various measures used in the non-adherence literature can be misleading for the unfamiliar reviewer. In this narrative review, a practical overview of important considerations for interpreting adherence endpoints and measures is discussed. Also, an organizational framework is proposed to consider published adherence interventions. This framework may allow for a unique appreciation into areas of limited knowledge and thus highlights targets for future research. © 2013 Blackburn et al, publisher and licensee Dove Medical Press Ltd.




Blackburn, D. F., Swidrovich, J., & Lemstra, M. (2013, January). Non-adherence in type 2 diabetes: Practical considerations for interpreting the literature. Patient Preference and Adherence.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free