The Relationship of UGT2B15 Pharmacogenetics and Lorazepam for Anxiety

  • Ching N
  • Alzghari A
  • Alzghari S
N/ACitations
Citations of this article
19Readers
Mendeley users who have this article in their library.

Abstract

Anxiety affects over 260 million people worldwide. Benzodiazepines are a class of agents used in combination with other therapies for the management of anxiety. Lorazepam is a commonly prescribed benzodiazepine metabolized by uridine 5'-diphosphate-glucuronosyltransferases. Herein, we discuss recent findings regarding the pharmacogenetics of uridine 5'-diphosphate-glucuronosyltransferase 2B15 (UGT2B15), lorazepam, and its role in the treatment of anxiety.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Ching, N. R., Alzghari, A. K., & Alzghari, S. K. (2018). The Relationship of UGT2B15 Pharmacogenetics and Lorazepam for Anxiety. Cureus. https://doi.org/10.7759/cureus.3133

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 1

50%

Researcher 1

50%

Readers' Discipline

Tooltip

Pharmacology, Toxicology and Pharmaceut... 2

33%

Biochemistry, Genetics and Molecular Bi... 2

33%

Chemistry 1

17%

Neuroscience 1

17%

Save time finding and organizing research with Mendeley

Sign up for free