ArticleOPEN ACCESS

AGE-RAGE interaction and oxidative stress in obesity-related renal dysfunction

Kidney International
DOI: 10.1038/ki.2011.86
27Citations
Citations of this article
40Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Obesity is a risk factor for development of kidney disease. Advanced glycation end products (AGEs) and the receptor for AGEs (RAGE) play important roles in the pathogenesis of renal disorders that are not associated with diabetes. Harcourt et al. provide evidence to support the mechanism responsible for AGE-RAGE interaction and the downstream oxidative stress and inflammation in obesity-related dysfunction. These findings might provide a new strategy for kidney disease in obesity. © 2011 International Society of Nephrology.

Cite

CITATION STYLE

APA

Tomino, Y., Hagiwara, S., & Gohda, T. (2011, July 2). AGE-RAGE interaction and oxidative stress in obesity-related renal dysfunction. Kidney International. Nature Publishing Group. https://doi.org/10.1038/ki.2011.86

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free