A new pentacyclic triterpenoid glucoside from Prunus serrulata var. spontanea

Abstract

A new triterpenoid, 2α,3α,24-trihydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (4) along with four known triterpenoids, ursolic acid (1), 2α-hydroxyursolic acid (2), 2α,3α,24- trihydroxyurs-12-en-28-oic acid (3), and 2α,3α,19α,24- tetrahydroxyurs-12-en-28-oic acid-28-O-β-D-glucopyranosyl ester (5), were isolated from the leaves of Prunus serrulata var. spontanea (Rosaceae). Compounds 3 - 5 showed ONOO- scavenging activity, whereas compounds 1 and 2 were virtually inactive. © 2004 Pharmaceutical Society of Japan.