Mitochondria in aging: A review of structure, function, and interorganelle relationships

Abstract

The process of aging is what everyone is experiencing during the whole life. Many factors contribute to the aging process, among which the changes in mitochondrial structure and function are one important step. in this review, we elaborated on the relationship between mitochondria and aging from three aspects: the structure and function of mitochondria, the changes of mitochondria during aging, and the relationship between mitochondria and other organelles, we also described the progress related to mitochondrial targeted therapy. In summary, The passage highlights a review that examines the connection between mitochondria and aging from three main angles: understanding the structure and function of mitochondria, exploring how mitochondria change as an individual ages, and uncovering their relationships with other cellular organelles. Additionally, the passage discusses the advancements in mitochondrial targeted therapy within the context of aging.