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Protactin, a new antibiotic metabolite and a possible precursor of the actinomyces

The Journal of Antibiotics (1992) 45(1) 20-28
DOI: 10.7164/antibiotics.45.20
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Abstract

Streptomyces cucumerosporus strain L703-4 (ATCC 53784) produces a new 4-methyl-3-hydroxyanthraniloylpentapeptide lactone for which we have proposed the name protactin, in addition to several actinomycin components. Protactin is rather resistant to air oxidation but it can be converted to a new actinomycin, actinomycin Zp by ferricyanide oxidation. Actinomycin Zp possesses in vitro antibacterial activity and in vivo antitumor activity against P-388 leukemia in mice. © 1992, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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CITATION STYLE

APA

Hanada, M., Sugawara, K., Nlshiyama, Y., Kamei, H., Hatori, M., & Konishi, M. (1992). Protactin, a new antibiotic metabolite and a possible precursor of the actinomyces. The Journal of Antibiotics, 45(1), 20–28. https://doi.org/10.7164/antibiotics.45.20

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