P-Stereodefined oligodeoxyribonucleoside boranophosphates (PB-ODNs) were successfully synthesized by the conversion of diastereopure H-phosphonate intermediates. Thermal denaturation studies clearly showed that the duplex stability of PB-ODNs with the complementary DNA and RNA depends on the stereochemistry of the boranophosphate linkages.
CITATION STYLE
Iwamoto, N., Oka, N., & Wada, T. (2009). Stereocontrolled synthesis of oligodeoxyribonucleoside boranophosphates via stereodefined H-phosphonate intermediates. Nucleic Acids Symposium Series (2004), (53), 9–10. https://doi.org/10.1093/nass/nrp005
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