Abstract
A series of monoclonal antibodies (MAbs), specific for Mycobacterium bovis and BCG strains, were tested extensively for cross-reactivity to a wide range of mycobacterial species using ELISA, Western blotting and dot-blot analysis. The MAbs bound specifically to M. bovis and BCG and showed limited cross-reactivity with some strains of M. tuberculosis. All these MAbs recognized a 22 kDa protein previously termed MPB70, and by competitive ELISA analysis appeared to detect at least three M. bovis-specific determinants on the MPB70 molecule.
Cite
CITATION STYLE
Wood, P. R., Ripper, J., Radford, A. J., Bundesen, P. G., Rylatt, D. B., Cottis, L. E., … Plackett, P. (1988). Production and characterization of monoclonal antibodies specific for Mycobacterium bovis. Journal of General Microbiology, 134(9), 2599–2604. https://doi.org/10.1099/00221287-134-9-2599
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
