R453Plus1Toolbox: An R/Bioconductor package for analyzing Roche 454 sequencing data

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Abstract

The R453Plus1Toolbox is an R/Bioconductor package for the analysis of 454 Sequencing data. Projects generated with Roche's data analysis software can be imported into R allowing advanced and customized analyses within the R/Bioconductor environment for sequencing data. Several methods were implemented extending the current functionality of Roche's software. These extensions include methods for quality assurance and annotation of detected variants. Further, a pipeline for the detection of structural variants, e.g. balanced chromosomal translocations, is provided. © The Author 2011. Published by Oxford University Press. All rights reserved.

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Klein, H. U., Bartenhagen, C., Kohlmann, A., Grossmann, V., Ruckert, C., Haferlach, T., & Dugas, M. (2011). R453Plus1Toolbox: An R/Bioconductor package for analyzing Roche 454 sequencing data. Bioinformatics, 27(8), 1162–1163. https://doi.org/10.1093/bioinformatics/btr102

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