Cerebrospinal fluid GABA levels in various neurological and psychiatric diseases

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Abstract

Cerebrospinal fluid gamma-aminobutyric acid (CSF-GABA) was analysed by radioreceptor assay in 16 normal controls and 84 patients with various neurological and psychiatric diseases. In patients with spinocerebellar degeneration, neuro-Behcet's syndrome and Parkinson's disease, CSF-GABA levels were decreased. On the other hand, increased CSF-GABA levels were detected in patients with meningitis.

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Kuroda, H., Ogawa, N., Yamawaki, Y., Nukina, I., Ofuji, T., Yamamoto, M., & Otsuki, S. (1982). Cerebrospinal fluid GABA levels in various neurological and psychiatric diseases. Journal of Neurology Neurosurgery and Psychiatry, 45(3), 257–260. https://doi.org/10.1136/jnnp.45.3.257

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