A case of papillary glioneuronal tumor

Abstract

Papillary glioneuronal tumors (PGNT) are a rare tumor type, which were only recently recognized and histologically characterized by their pseudopapillary architecture associated with compact areas composed of neuronal elements in different maturation states. The authors present 17-year-old woman with papillary glioneuronal tumor. She was admitted to our institute because of a temporal mass discovered accidentally. Imaging showed a demarcated, mainly solid and partly cystic subcortical tumor in the right temporal lobe. The patient underwent surgery for total resection of the lesion. Histologically, it was a biphasic tumor characterized by small cuboidal GFAP-positive astrocytes around hyalinised blood vessels and synaptophysin-positive interpapillary collections of neurocytes. After surgery, she remains asymptomatic with no tumor recurrence at her one-year follow-up.