Methyl 3-(2-chlorophenyl)-2-(1H-indol-3-ylmethyl)-5-[1-(4-methoxyphenyl)-4- oxo-3-phenylazetidin-2-yl]-4-nitropyr-rolidine-2-carboxylate

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Abstract

In the mol-ecule of the title compound, C37H33ClN4O6, the four-membered Β-lactam ring is essentially planar and is oriented at dihedral angles of 30.0 (1), 76.3 (1) and 30.9 (1)° with respect to the methoxy-phenyl ring, the phenyl ring and the indole unit, respectively. The pyrrolidine ring adopts a twist conformation. Intra-molecular C - H⋯Cl and C - H⋯O hydrogen bonds result in the formation of two five- and one six-membered rings. In the crystal structure, inter-molecular C - H⋯O and N - H⋯O hydrogen bonds link the mol-ecules. A weak π⋯π inter-action between the pyrrole rings further stabilizes the structure, with a centroid-centroid distance of 3.806 (2) Å.

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Nirmala, S., Kamala, E. T. S., Sudha, L., Arumugam, N., & Raghunathan, R. (2008). Methyl 3-(2-chlorophenyl)-2-(1H-indol-3-ylmethyl)-5-[1-(4-methoxyphenyl)-4- oxo-3-phenylazetidin-2-yl]-4-nitropyr-rolidine-2-carboxylate. Acta Crystallographica Section E: Structure Reports Online, 64(6). https://doi.org/10.1107/S1600536808013585

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