Abstract
We present evidence for the toxic effects of fatty acid 18:5n3 (octadecapentaenoic acid) in the gills and intestine of the sea bass Dicentrarchus labrax. Light microscopic observation of gills showed strong mucus production and alteration of ionocytes. The Mg- and Na,K-ATPase activities were inhibited, with IC50 values of 10-3 and 1.6 x 10-4 M, respectively. Results are discussed in relation to osmoregulation.
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Sola, F., Masoni, A., Fossat, B., Porthé-Nibelle, J., Gentien, P., & Bodennec, G. (1999). Toxicity of fatty acid 18:5n3 from Gymnodinium cf. mikimotoi: I. morphological and biochemical aspects on Dicentrarchus labrax gills and intestine. Journal of Applied Toxicology, 19(4), 279–284. https://doi.org/10.1002/(SICI)1099-1263(199907/08)19:4<279::AID-JAT579>3.0.CO;2-X
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