Abstract
Recently, radiation induced necrosis in the brain has been treated using bevacizumab, an anti-VEGF antibody. We validated the VEGF specificity by comparing the therapeutic efficacy of anti-VEGF with non-specific isotype control antibody. Additionally, we found that VEGF over-expression and RN developed simultaneously, which precludes preventative anti-VEGF treatment.
Author supplied keywords
Cite
CITATION STYLE
APA
Perez-Torres, C. J., Yuan, L., Schmidt, R. E., Rich, K. M., Drzymala, R. E., Hallahan, D. E., … Garbow, J. R. (2015). Specificity of vascular endothelial growth factor treatment for radiation necrosis. Radiotherapy and Oncology, 117(2), 382–385. https://doi.org/10.1016/j.radonc.2015.09.004
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
Already have an account? Sign in
Sign up for free