Wavelet multiresolution analysis and dyadic scalogram for detection of epileptiform paroxysms in electroencephalographic signals

Abstract

Introduction: Early detection of epilepsy by the review of large electroencephalographic (EEG) recordings is very stressful, time-consuming, and subjective for neurologists. Several automatic seizure detection systems have been proposed in the literature to solve this problem. Methods: This study proposes two complementary wavelet‑based approaches for detecting epileptiform paroxysms in EEG signals. First methodology applied the wavelet multiresolution analysis (MRA) to filter non-epileptiform activity in long-term EEG. Second methodology used the wavelet dyadic scalogram to analyze which scales were related to the epileptiform paroxysms. For tests, 65 wavelet functions were selected between daubechies, biorthogonal, symlets, reverse biorthogonal and coiflet wavelet families in order to evaluate their performance. Results: For MRA, it was noted a better performance by using the db4 function, by reaching 48.30% of energy with 8 wavelet coefficients, 0.717658 of correlation and 36.799 of root mean square error (RMSE). For wavelet dyadic scalograms, were chosen bior3.9 and rbio1.5 functions, by reaching 77.98% of sensitivity, 94.08% of specificity, 87.87% of efficiency and 0.9613 of area under the curve (AUC value) by using bior3.9. Conclusion: The presented approaches are highly complementary for a whole automatic seizure detection system by using the MRA as pre-processing stage to filter non-epileptiform activity, and wavelet dyadic scalogram for extracting desired features from filtered EEG signals.