Selective consumption of large platelets during massive bleeding

Abstract

To see whether selective consumption of either small or large platelets occurs during haemostasis in vivo the mean platelet volume was studied in six patients who developed thrombocytopenia after trauma. The mean platelet volume at the onset of thrombocytopenia was significantly lower than that on admission (p>001): selective loss of large platelets had occurred. © 1985, British Medical Journal Publishing Group. All rights reserved.