Analgesic activity of bacosine, a new triterpene isolated from Bacopa monnieri

Abstract

Bacosine (1) isolated from the aerial parts of Bacopa monnieri, exhibited moderate analgesic effects but was found to be devoid of effects on barbiturate narcosis, haloperidol-induced catalepsy, spontaneous motor activity (SMA) and conditioned avoidance response (CAR). The analgesic effects, reported for the first time in this plant, were found to be opioidergic in nature.