Radionuclide therapy

Abstract

Prior to all radionuclide therapy procedures a diagnostic scan is performed and written informed consent is requested from patient Radioactive iodine (I-131) is an excellent method of treating overactive thyroid tissue (either diffuse or toxic nodular goitre) In majority of patients with differentiated thyroid cancer (tumour size of 1cm or more), I-131 is the treatment of choice after total thyroidectomy Bone pain from osteoblastic bone metastases can be ameliorated 45-90% of the time using strontium-89 (89Sr) and samarium-153 (153SM) B-cell NHL have proven most responsive to radiolabelled monoclonal antibody theray because they are particularly susceptible to radiation induced apoptosis.