Recent Advances in Salivary Glucose Monitoring

Abstract

Diabetes is a worldwide public healthcare issue that poses a significant threat to human health. Currently, diabetic patients rely primarily on invasive blood glucose monitoring, which causes tremendous suffering. In recent years, noninvasive glucose monitoring has been the focus of research, especially with saliva sensors. This review systematically illustrates the latest research progress of electrochemical glucose sensors, and the principles of saliva monitoring of blood glucose, and presents the relevant challenges faced and strategies to cope with them. In addition, material design and practical applications for salivary glucose monitoring such as mouth guards, pacifiers, etc. are presented. This review aims to promote the development and possible future commercialization of salivary glucose monitoring to improve the management of diabetes.