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PPL-catalysed hydrolysis of 3,4-disubstituted β-lactams: Effect of chain length and stereochemistry on the enantioselectivity

Tetrahedron (1998) 54(23) 6529-6538
DOI: 10.1016/S0040-4020(98)00313-5
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Abstract

3,4-Disubstituted β-lactam acetates 1a-15a have been subjected to PPL- catalysed hydrolysis. The stereochemical course of hydrolysis has been shown to depend upon the C3-C4 relative stereochemistry and the length of the chain bearing acetate functionality.

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Basak, A., Bhattacharya, G., & Bdour, H. M. M. (1998). PPL-catalysed hydrolysis of 3,4-disubstituted β-lactams: Effect of chain length and stereochemistry on the enantioselectivity. Tetrahedron, 54(23), 6529–6538. https://doi.org/10.1016/S0040-4020(98)00313-5

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