In vivo protection against Leishmania mexicana mediated by monoclonal antibodies.

Abstract

In these experiments we have added to the concept of the importance of antibody in the resistance of Leishmania infection by demonstrating that stage- and species-specific monoclonal antibodies to external membrane components of L. mexicana promastigotes can confer complete protection when inoculated with L. mexicana promastigotes into BALB/c mice foot pads.