Electrical stimulation for modification of memory and cognition

Abstract

A major challenge in neuroscience research is to develop stimulation systems (both minimally invasive and noninvasive) that can safely, flexibly and efficiently tap into the human brain, to coordinate complex cognitive and behavioral tasks. In this regard, neural technology is targeting new therapeutic approaches to improve mental performance for patients with cognitive disorders. Herein, we discuss recent developments in electro-stimulation therapies that have been instrumental in improving memory and cognition, including working memory, decision making and executive control, by enhancing cognitive performance. The use of various stimulation devices and technologies developed recently is examined in terms of preclinical (nonhuman primate experiments) and clinical applications to human brain disorders.