Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019

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Abstract

The Finnish new variant of Chlamydia trachomatis (FI-nvCT) is escaping diagnostics in Finland, Norway and Sweden. We have developed and validated an Aptima-format nucleic acid amplification test (NAAT) designed specifically to detect the FI-nvCT. This NAAT has high sensitivity (100%) and specificity (100%) for the FI-nvCT strain, enabling further investigation of the geographic distribution, prevalence and transmission of this diagnostic-escape mutant in screening populations in Europe.

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Weinbaum, B., Williams, A., Hadad, R., Vinluan, B., Puolakkainen, M., Unemo, M., & Getman, D. (2020, February 6). Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019. Eurosurveillance. European Centre for Disease Prevention and Control (ECDC). https://doi.org/10.2807/1560-7917.ES.2020.25.5.2000038

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