Linkage mapping from pair-wise recombination data

Abstract

The problem of obtaining a genetic map of a linkage group from pair-wise recombination data is considered. A non-parametric approach is proposed, that does not require the definition of a mapping function, computation of coefficients of coincidence, nor knowledge of map length or sex differences in recombination. An application to Bridges and Morgan’s (1923) data on chromosome 3 of Drosophila melanogaster is presented. © 1977, The Genetical Society of Great Britain. All rights reserved.