Pregnancy complications and perinatal outcomes of women with hemoglobinopathies

Abstract

Objective: To estimate the prevalence of gestational complications and perinatal outcomes in women with and without hemoglobinopathies. Method: This is a cross-sectional study with a quantitative approach, performed from 110 medical records of pregnant women who underwent prenatal, childbirth, postpartum and perinatal care in a gynecology and obstetrics service of the University Hospital at the Federal University of Mato Grosso do Sul, Brazil, between 2010 and 2011. Results: Gestational complications in women with and without hemoglobinopathies in the variables: obstetric (preterm labor, pre-eclampsia, ruptured membranes for more than six hours (17.06 times; 12.19 times; 4.27 times respectively); clinical: urinary tract infection, heart failure, severe anemia (2.97 times; 12.6 times;  9.75 times, respectively), and perinatal: cesarean delivery, neonatal infection; the newborn in the neonatal intensive care unit; fetal death, stillbirth (1.57 times; 39.00 times; 12.19 times; 12.9 times; 9.75 times; respectively) were higher in the presence of hemoglobinopathies. Conclusion: The pregnancy outcomes of women with hemoglobinopathies, perinatal and their newborns showed a higher prevalence of complications than women without this change. Keywords: Hemoglobinopathies; Pregnancy Complications, Hematologic; Perinatal Care.