Multiple system atrophy - Clinical-radiological correlation: Report of two cases

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Abstract

Multiple system atrophy (MSA) is a sporadic, neurodegenerative disorder, clinically characterized by parkinsonian, autonomic, cerebellar and pyramidal signs. We describe two patients showing different presentations of the same disease. The patient on case 1 presents features of MSA-C or olivopontocerebellar atrophy with the pontine "cross sign" on brain MRI. The second case reports a patient presenting MSA-P or striatonigral degeneration and the brain MRI shows lenticular nucleus sign alteration. We think that brain MRI might increase the accuracy diagnostic of MSA.

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De Albuquerque, A. V., De Freitas, M. R. G., Cincinatus, D., & Harouche, M. B. B. (2007). Multiple system atrophy - Clinical-radiological correlation: Report of two cases. Arquivos de Neuro-Psiquiatria, 65(2 B), 512–515. https://doi.org/10.1590/s0004-282x2007000300029

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