The Finding of N-Nitrosodimethylamine in Common Medicines

  • Adamson R
  • Chabner B
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Abstract

The FDA has ordered the withdrawal of all ranitidine products from the marketplace based on recent findings of increased and unacceptable levels of N-nitrosodimethylamine (NDMA). This commentary reviews the sources and properties of NDMA, assesses the dangers it poses, and suggests measures to mitigate contamination.

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Adamson, R. H., & Chabner, B. A. (2020). The Finding of N-Nitrosodimethylamine in Common Medicines. The Oncologist, 25(6), 460–462. https://doi.org/10.1634/theoncologist.2020-0142

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