4′-O-methylglycosylation of curcumin by Beauveria bassiana

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Abstract

The applications of curcumin have been limited by its poor water solubility and low bioavailability. In this study, we successfully synthesized a new curcumin derivative, curcumin-8′-O-4″-O-methyl-β-D- glucopyranoside, by biotransformation with the fungal strain Beauveria bassiana ATCC 7159. The structure of this new product was determined on the basis of spectroscopic data. This is the first record of a curcumin glycoside that has been synthesized by a fungus.

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Zeng, J., Yang, N., Li, X. M., Shami, P. J., & Zhan, J. (2010). 4′-O-methylglycosylation of curcumin by Beauveria bassiana. Natural Product Communications, 5(1), 77–80. https://doi.org/10.1177/1934578x1000500119

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