Synthesis of functionalized benzobarrelenes and azabenzobarrelenes by rhodium-catalyzed [2+2+2] cycloaddition

Abstract

It has been established that a cationic rhodium(I)/H8-BINAP complex catalyzes the [2+2+2] cycloaddition of cyclohexadiene-linked 1,7-diynes with monoynes to produce functionalized benzobarrelenes. Functionalized azabenzobarrelenes were also obtained by using BINAP as a ligand and nitriles as coupling partners.