Association of Obesity with Cognitive Impairment and Depression among Oldest Old Population having Frailty syndrome

Abstract

Objectives: The objectives were to estimate prevalence of obesity among frail individuals aged =80 years and examine the association of obesity with cognitive impairment and depression among frail individuals aged =80 years. Methods: Twohundred community-dwelling participants aged =80 years, were enrolled; 166 frail participants were further analyzed. Obesity and adiposity were determined by Body Mass Index (BMI), Waist Circumference (WC) and Body Fat Percentage (BF%). Cognitive impairment and Depression were assessed using Mini Mental State Examination (MMSE) and Geriatric Depression Scale (GDS-15). Frailty was assessed by Fried criteria. Chi-Square, t-test, trend-analysis and Logistic Regression (LR) were done. Results: Obesity among Frail individuals aged =80 years was 40% using BMI and 73.2% using WC. Obesity was inversely associated with cognitive impairment and depression among frail individuals. Severity of cognitive impairment and depression was lower among obese frail than no