Expedient synthesis of 8-aza-1-hydroxy-2,3-dioxabicyclo[4.3.0]nonan-7-ones using manganese(III)-catalyzed aerobic oxidation

Abstract

The reaction of 3-alkyl-2,4-pyrrolidinediones with 1,1-diarylethenes in the presence of a catalytic amount of manganese(III) acetate resulted in the aerobic endoperoxidation that produced very stable crystalline 8-aza-1-hydroxy-2,3-dioxabicyclo[4.3.0]nonan-7-ones in high yields. Copyright © by Walter de Gruyter.