Electrochemical determination of oncocalyxone A using an iron-phthalocyanine/iron-porphyrin modified glassy carbon electrode

Abstract

The development of a highly sensitive voltammetric sensor for oncocalyxone A using a glassy carbon electrode modified with a bilayer iron(II) tetrasulfonated phthalocyanine (FeTSPc) and iron(III) tetra-(N-methyl-4-pyridyl) -porphyrin (FeT4MPyP) is described. The modified electrode showed high catalytic activity and stability for the oncocalyxone A reduction, provoking the anodic shift of the reduction peak potentials of ca. 30 mV and presenting much higher peak currents than those obtained on the bare GC electrode. A wide linear response range between 0.005-1.2 μmol L -1, with a sensitivity of 8.11 μA L μmol-1 and limits of detection (LOD) and quantification (LOQ) of 1.5 and 5 nmol L -1 were obtained with this sensor. ©2008 Sociedade Brasileira de Química.