Abstract
A new calcium blocker, designated leualacin, has been isolated from Hapsidospora irregularis. The compound inhibits the binding of 3H-nitrendipine, a well known synthetic calcium blocker, to cardiac Ca channel in a competitive manner, although its structure is completely different from dihydropyridines. © 1992, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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CITATION STYLE
Hamano, K., Furuya, K., Miyamoto, M., Takamatsu, Y., Hemmi, A., & Tanzawa, K. (1992). Leualacin, a novel calcium blocker from hapsidospora irregularis: I. Taxonomy, fermentation, isolation, physico-chemical and biological properties. The Journal of Antibiotics, 45(6), 899–905. https://doi.org/10.7164/antibiotics.45.899
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