Biological and chemical characterization of lipopolysaccharide from Selenomonas spp. in human periodontal pockets

Abstract

Pure lipopolysaccharide extracted from Selenomonas spp. isolated from human periodontal pockets was composed of 23.7% carbohydrate, 16.5% hexosamine, 1.2% 2-keto-3-deoxyoctonate, 0.7% heptose, 26.0% lipid, 1.8% protein, and 1.3% phosphorus. It was shown to be quite lethal, to have very active pyrogenicity, to give a typical biphasic-fever response, and to produce a positive local Shwartzman reaction.