Molecular genetics related to non-Hodgkin lymphoma

Abstract

Non-Hodgkin lymphoma (NHL) is a serious disease, with a high proportion of mortality. Molecular genetic abnormalities are very common in NHL, but specific characterization in accordance to molecular genetics for lymphoma subtypes is not yet completed. This article summarizes the relationship between B- and T-NHL and molecular genetics. We focus on NHL subtypes and emphasize its features to figure out what is exposed about NHL genetics. The basis of this method is collection of biological specimens for genomic and genetic analyses. This summary may help to prompt prediction of outcomes and guide therapy in the future.