Abstract
Extrinsic nociceptor neurons mediate protection from Salmonella infection by direct sensing and release of CGRP, which leads to suppression of M cell density and maintenance of SFB colonization of the ileum.
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Lai, N. Y., Musser, M. A., Pinho-Ribeiro, F. A., Baral, P., Jacobson, A., Ma, P., … Chiu, I. M. (2020). Gut-Innervating Nociceptor Neurons Regulate Peyer’s Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell, 180(1), 33-49.e22. https://doi.org/10.1016/j.cell.2019.11.014
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