Antioxidant, antimicrobial, and cytotoxic properties of Aniba parviflora essential oils from the Amazon

Abstract

Essential oils (EOs) from leaves and branches of Aniba parviflora (Meisn.) Mez were obtained by hydrodistillation and their chemical compositions determined by gas chromatography - mass spectrometry. Oxygenated sesquiterpenoids were the most representative compound class in both EOs (40%). However, the leaf EO was rich in β-phellandrene (15.1%), linalool (14.1%), and ≈-eudesmol (12.9%). The EO from the branches showed high concentrations of ≈-eudesmol (16.8%), β-caryophyllene (15.7%), linalool (12.4%), β-phellandrene (6.7%), and bicyclogermacrene (6.0%). The EOs were screened for radical-scavenging activity using the DPPH assay. In the DPPH assay, the EOs showed an antioxidant activity with TEAC values of 296.8 ± 20.2 and 357.3 ± 43.8 mg.TE.mL-1, about one-Third that of the Trolox standard. The EOs were subjected to antibacterial screening and displayed promising activity against Escherichia coli (MIC < 19.5 μg.mL-1). In addition, the EOs were tested for cytotoxic activity against MCF-7 breast tumor cells and the leaf EO (IC50 = 67.9 ± 3.0 μg.mL-1) was more active than that from the branches (IC50 = 102.2 ± 3.0 μg.mL-1).