Proximal coronary vasomotor reactivity after exercise training in dogs

Abstract

The effects of exercise on large coronary vasoreactivity were determined in 8 dogs trained by treadmill running for 8 weeks. Six nontrained dogs comprised the control group. The trained group showed a significant reduction in heart rate during graded submaximal exercise testing when compared with the controls, and resting plasma levels of norepinephrine (nontrained group, 331 ± 99 pg/ml; trained group, 142 ± 30 pg/ml; p