Acid-catalyzed reaction of 1-(2,2-dimethoxyethyl)ureas with phenols as an effective approach to diarylethanes and dibenzoxanthenes

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Abstract

A one-pot synthesis of urea-substituted diarylethanes and dibenzoxanthenes starting from 1-(2,2-dimethoxyethyl)ureas and phenols has been developed. The approach uses readily available reagents and catalysts, requires mild reaction conditions and provides the target compounds in good to high yields.

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Smolobochkin, A. V., Gazizov, A. S., Voronina, J. K., Rizbayeva, T. S., Burilov, A. R., & Pudovik, M. A. (2019). Acid-catalyzed reaction of 1-(2,2-dimethoxyethyl)ureas with phenols as an effective approach to diarylethanes and dibenzoxanthenes. Arkivoc, 2019(6), 180–189. https://doi.org/10.24820/ark.5550190.p011.055

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