Myc-modulated miR-9 makes more metastases

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Abstract

The microRNA miR-9 is induced by Myc in breast cancer cells where it targets the major epithelial adherens junction protein, E-cadherin. This primes the cancer cells for epithelial-mesenchymal transition (EMT) and also stimulates angiogenesis in tumours. © 2010 Macmillan Publishers Limited. All rights reserved.

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Khew-Goodall, Y., & Goodall, G. J. (2010, March). Myc-modulated miR-9 makes more metastases. Nature Cell Biology. https://doi.org/10.1038/ncb0310-209

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