Abstract
DNA microarray in 22 patients with acute leukemia revealed genes which were differentially expressed. Ribosomal protein SA (RPSA), minichromosome maintenance deficient 2 (MCM2) and heterogeneous nuclear ribonucleoprotein A1 (HNRPA1) were significantly upregulated (p<0.05, t test) in refractory patients, suggesting that they may play a role in refractoriness in acute leukemia and could be biomarkers of prognosis.
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Wei, Q., Li, Y., Chen, L., Zhang, L., He, X., Fu, X., … Mao, Y. (2006). Genes differentially expressed in responsive and refractory acute leukemia. Frontiers in Bioscience, 11(1 P.889-1198), 977–982. https://doi.org/10.2741/1854
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