Polymer pen lithography (PPL)-induced site-specific click chemistry for the formation of functional glycan arrays

Abstract

Polymer pen lithography (PPL) can be combined with the Cu I-catalyzed azide-alkyne click reaction to create molecular arrays with control over orientation and sub-1 μm feature sizes over cm2 areas. The process has been applied to the deposition of carbohydrates to form functional glycochips. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.