Axon growth inhibition: Signals from the p75 neurotrophin receptor

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Abstract

Axon growth after CNS injury is restricted in part by several inhibitors found in myelin. The inhibition requires interaction of the Nogo receptor with the p75 neurotrophin receptor. A new paper now shows that the Rho inhibitor Rho-GDIα mediates this signaling.

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Kaplan, D. R., & Miller, F. D. (2003, May 1). Axon growth inhibition: Signals from the p75 neurotrophin receptor. Nature Neuroscience. https://doi.org/10.1038/nn0503-435

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