Adjusted Multidisciplinary Treatment Against Multiple Colorectal Liver Metastasis May Expand Indication of Intensive Treatment to Previously Excluded Elderly Patients

Abstract

Colorectal carcinoma (CRC) is one of the most common causes of cancer-related mortalities, and liver metastases comprise the most frequently encountered distant metastases, which generally occur synchronously and metachronously with the rate of 10% and 15%, respectively. Recent development of various less invasive therapeutic approach against CRC, including laparoscopic operative procedures, radiofrequency ablation, and modified chemotherapy regimen not only improve the patients’ quality of life and survival, but also expand indication of intensive treatment to previously excluded elderly patients with reduced performance status. We focused on the feasibility and current status of adjusted multidisciplinary approach to multiple CRC liver metastases through a successfully treated elderly case with reduced performance status.